Assessment of Single Cell RNA-Seq Normalization Methods

We have assessed the performance of seven normalization methods for single cell RNA-seq using data generated from dilution of RNA samples. Our analyses showed that methods considering spike-in External RNA Control Consortium (ERCC) RNA molecules significantly outperformed those not considering ERCCs...

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Detalles Bibliográficos
Autores principales: Ding, Bo, Zheng, Lina, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499114/
https://www.ncbi.nlm.nih.gov/pubmed/28468817
http://dx.doi.org/10.1534/g3.117.040683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499114/
https://www.ncbi.nlm.nih.gov/pubmed/28468817
http://dx.doi.org/10.1534/g3.117.040683

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