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Assessment of Single Cell RNA-Seq Normalization Methods
We have assessed the performance of seven normalization methods for single cell RNA-seq using data generated from dilution of RNA samples. Our analyses showed that methods considering spike-in External RNA Control Consortium (ERCC) RNA molecules significantly outperformed those not considering ERCCs...
Autores principales: | Ding, Bo, Zheng, Lina, Wang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499114/ https://www.ncbi.nlm.nih.gov/pubmed/28468817 http://dx.doi.org/10.1534/g3.117.040683 |
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