Novel Mutations in Synaptic Transmission Genes Suppress Neuronal Hyperexcitation in Caenorhabditis elegans

Acetylcholine (ACh) receptors (AChR) regulate neural circuit activity in multiple contexts. In humans, mutations in ionotropic acetylcholine receptor (iAChR) genes can cause neurological disorders, including myasthenia gravis and epilepsy. In Caenorhabditis elegans, iAChRs play multiple roles in the...

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Detalles Bibliográficos
Autores principales: McCulloch, Katherine A., Qi, Yingchuan B., Takayanagi-Kiya, Seika, Jin, Yishi, Cherra, Salvatore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499116/
https://www.ncbi.nlm.nih.gov/pubmed/28468816
http://dx.doi.org/10.1534/g3.117.042598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499116/
https://www.ncbi.nlm.nih.gov/pubmed/28468816
http://dx.doi.org/10.1534/g3.117.042598

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