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Validated Bayesian Differentiation of Causative and Passenger Mutations

In many contexts, the problem arises of determining which of many candidate mutations is the most likely to be causative for some phenotype. It is desirable to have a way to evaluate this probability that relies as little as possible on previous knowledge, to avoid bias against discovering new genes...

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Detalles Bibliográficos
Autores principales: Cross, Frederick R., Breker, Michal, Lieberman, Kristi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499118/
https://www.ncbi.nlm.nih.gov/pubmed/28526731
http://dx.doi.org/10.1534/g3.117.039016