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Validated Bayesian Differentiation of Causative and Passenger Mutations
In many contexts, the problem arises of determining which of many candidate mutations is the most likely to be causative for some phenotype. It is desirable to have a way to evaluate this probability that relies as little as possible on previous knowledge, to avoid bias against discovering new genes...
Autores principales: | Cross, Frederick R., Breker, Michal, Lieberman, Kristi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499118/ https://www.ncbi.nlm.nih.gov/pubmed/28526731 http://dx.doi.org/10.1534/g3.117.039016 |
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