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Essential Function of the Serine Hydroxymethyl Transferase (SHMT) Gene During Rapid Syncytial Cell Cycles in Drosophila

Many metabolic enzymes are evolutionarily highly conserved and serve a central function in the catabolism and anabolism of cells. The serine hydroxymethyl transferase (SHMT) catalyzing the conversion of serine and glycine and vice versa feeds into tetrahydrofolate (THF)-mediated C1 metabolism. We id...

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Detalles Bibliográficos
Autores principales: Winkler, Franziska, Kriebel, Maria, Clever, Michaela, Gröning, Stephanie, Großhans, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499137/
https://www.ncbi.nlm.nih.gov/pubmed/28515048
http://dx.doi.org/10.1534/g3.117.043133