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Epalrestat tetra­hydro­furan monosolvate: crystal structure and phase transition

The title compound, epalrestat {systematic name: (5Z)-5-[(2E)-2-methyl-3-phenyl­prop-2-en-1-yl­idene]-4-oxo-2-sulfanyl­idene-1,3-thia­zolidine-3-acetic acid}, crystallized as a tetra­hydro­furan monosolvate, C(15)H(13)NO(3)S(2)·C(4)H(8)O. Epalrestat, an important drug for diabetic neuropathy, has be...

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Detalles Bibliográficos
Autores principales: Umeda, Daiki, Putra, Okky Dwichandra, Gunji, Mihoko, Fukuzawa, Kaori, Yonemochi, Etsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499264/
https://www.ncbi.nlm.nih.gov/pubmed/28775856
http://dx.doi.org/10.1107/S2056989017007976