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Epalrestat tetrahydrofuran monosolvate: crystal structure and phase transition
The title compound, epalrestat {systematic name: (5Z)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidine-3-acetic acid}, crystallized as a tetrahydrofuran monosolvate, C(15)H(13)NO(3)S(2)·C(4)H(8)O. Epalrestat, an important drug for diabetic neuropathy, has be...
Autores principales: | Umeda, Daiki, Putra, Okky Dwichandra, Gunji, Mihoko, Fukuzawa, Kaori, Yonemochi, Etsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499264/ https://www.ncbi.nlm.nih.gov/pubmed/28775856 http://dx.doi.org/10.1107/S2056989017007976 |
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