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Crystal structure of naltrexone chloride solvates with ethanol, propan-2-ol, and 2-methyl­propan-2-ol

Naltrexone [systematic name: 17-(cyclo­propyl­meth­yl)-3,14-di­hydroxy-4,5α-epoxymorphinan-6-one] is an opioid receptor competitive antagonist that has been widely used to prevent relapse in opioid- and alcohol-dependent subjects. Its chloride salt forms non-isomorphic solvates with ethanol (C(20)H(...

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Detalles Bibliográficos
Autores principales: Menze, Aveary R., Sinnott, Jefferson P., Nazarenko, Alexander Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499280/
https://www.ncbi.nlm.nih.gov/pubmed/28775872
http://dx.doi.org/10.1107/S205698901700843X