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The 2-μm plasmid encoded protein Raf1 regulates both stability and copy number of the plasmid by blocking the formation of the Rep1–Rep2 repressor complex

The 2-μm plasmid of the budding yeast Saccharomyces cerevisiae achieves a high chromosome-like stability with the help of four plasmid-encoded (Rep1, Rep2, Raf1 and Flp) and several host-encoded proteins. Rep1 and Rep2 and the DNA locus STB form the partitioning system ensuring equal segregation of...

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Detalles Bibliográficos
Autores principales: A. Rizvi, Syed M., Prajapati, Hemant K., Nag, Purba, Ghosh, Santanu K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499539/
https://www.ncbi.nlm.nih.gov/pubmed/28472368
http://dx.doi.org/10.1093/nar/gkx316