Identifying transposon insertions and their effects from RNA-sequencing data

Insertional mutagenesis using engineered transposons is a potent forward genetic screening technique used to identify cancer genes in mouse model systems. In the analysis of these screens, transposon insertion sites are typically identified by targeted DNA-sequencing and subsequently assigned to pre...

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Detalles Bibliográficos
Autores principales: de Ruiter, Julian R., Kas, Sjors M., Schut, Eva, Adams, David J., Koudijs, Marco J., Wessels, Lodewyk F. A., Jonkers, Jos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499543/
https://www.ncbi.nlm.nih.gov/pubmed/28575524
http://dx.doi.org/10.1093/nar/gkx461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499543/
https://www.ncbi.nlm.nih.gov/pubmed/28575524
http://dx.doi.org/10.1093/nar/gkx461

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