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Identifying transposon insertions and their effects from RNA-sequencing data
Insertional mutagenesis using engineered transposons is a potent forward genetic screening technique used to identify cancer genes in mouse model systems. In the analysis of these screens, transposon insertion sites are typically identified by targeted DNA-sequencing and subsequently assigned to pre...
Autores principales: | de Ruiter, Julian R., Kas, Sjors M., Schut, Eva, Adams, David J., Koudijs, Marco J., Wessels, Lodewyk F. A., Jonkers, Jos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499543/ https://www.ncbi.nlm.nih.gov/pubmed/28575524 http://dx.doi.org/10.1093/nar/gkx461 |
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