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Poly(A)-ClickSeq: click-chemistry for next-generation 3΄-end sequencing without RNA enrichment or fragmentation

The recent emergence of alternative polyadenylation (APA) as an engine driving transcriptomic diversity has stimulated the development of sequencing methodologies designed to assess genome-wide polyadenylation events. The goal of these approaches is to enrich, partition, capture and ultimately seque...

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Detalles Bibliográficos
Autores principales: Routh, Andrew, Ji, Ping, Jaworski, Elizabeth, Xia, Zheng, Li, Wei, Wagner, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499544/
https://www.ncbi.nlm.nih.gov/pubmed/28449108
http://dx.doi.org/10.1093/nar/gkx286