ChiPPI: a novel method for mapping chimeric protein–protein interactions uncovers selection principles of protein fusion events in cancer

Fusion proteins, comprising peptides deriving from the translation of two parental genes, are produced in cancer by chromosomal aberrations. The expressed fusion protein incorporates domains of both parental proteins. Using a methodology that treats discrete protein domains as binding sites for spec...

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Detalles Bibliográficos
Autores principales: Frenkel-Morgenstern, Milana, Gorohovski, Alessandro, Tagore, Somnath, Sekar, Vaishnovi, Vazquez, Miguel, Valencia, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Data Resources and Analyses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499553/
https://www.ncbi.nlm.nih.gov/pubmed/28549153
http://dx.doi.org/10.1093/nar/gkx423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499553/
https://www.ncbi.nlm.nih.gov/pubmed/28549153
http://dx.doi.org/10.1093/nar/gkx423

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