Modulation of cyclobutane thymine photodimer formation in T(11)-tracts in rotationally phased nucleosome core particles and DNA minicircles

Cyclobutane pyrimidine dimers (CPDs) are DNA photoproducts linked to skin cancer, whose mutagenicity depends in part on their frequency of formation and deamination. Nucleosomes modulate CPD formation, favoring outside facing sites and disfavoring inward facing sites. A similar pattern of CPD format...

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Detalles Bibliográficos
Autores principales: Wang, Kesai, Taylor, John-Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499554/
https://www.ncbi.nlm.nih.gov/pubmed/28525579
http://dx.doi.org/10.1093/nar/gkx427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499554/
https://www.ncbi.nlm.nih.gov/pubmed/28525579
http://dx.doi.org/10.1093/nar/gkx427

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