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Universal attenuators and their interactions with feedback loops in gene regulatory networks

Using a combination of mathematical modelling, statistical simulation and large-scale data analysis we study the properties of linear regulatory chains (LRCs) within gene regulatory networks (GRNs). Our modelling indicates that downstream genes embedded within LRCs are highly insulated from the vari...

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Detalles Bibliográficos
Autores principales: Liu, Dianbo, Albergante, Luca, Newman, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499555/
https://www.ncbi.nlm.nih.gov/pubmed/28575450
http://dx.doi.org/10.1093/nar/gkx485