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eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences

eIF5A is an essential protein involved in protein synthesis, cell proliferation and animal development. High eIF5A expression is observed in many tumor types and has been linked to cancer metastasis. Recent studies have shown that eIF5A facilitates the translation elongation of stretches of consecut...

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Detalles Bibliográficos
Autores principales: Pelechano, Vicent, Alepuz, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499558/
https://www.ncbi.nlm.nih.gov/pubmed/28549188
http://dx.doi.org/10.1093/nar/gkx479