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Coiled-coil interactions mediate serine integrase directionality

Serine integrases are bacteriophage enzymes that carry out site-specific integration and excision of their viral genomes. The integration reaction is highly directional; recombination between the phage attachment site attP and the host attachment site attB to form the hybrid sites attL and attR is e...

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Detalles Bibliográficos
Autores principales: Gupta, Kushol, Sharp, Robert, Yuan, Jimmy B., Li, Huiguang, Van Duyne, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499577/
https://www.ncbi.nlm.nih.gov/pubmed/28549184
http://dx.doi.org/10.1093/nar/gkx474