Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B mono-ubiquitination

Histone H2B lysine 120 mono-ubiquitination (H2Bub1) catalyzed by Rnf20 has been implicated in normal differentiation of embryonic stem (ES) and adult stem cells. However, it remains unknown how Rnf20 is recruited to its specific target chromosomal loci for the establishment of H2Bub1. Here, we revea...

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Detalles Bibliográficos
Autores principales: Lee, Bum-Kyu, Lee, Jiwoon, Shen, Wenwen, Rhee, Catherine, Chung, Haewon, Kim, Jonghwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499583/
https://www.ncbi.nlm.nih.gov/pubmed/28453857
http://dx.doi.org/10.1093/nar/gkx310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499583/
https://www.ncbi.nlm.nih.gov/pubmed/28453857
http://dx.doi.org/10.1093/nar/gkx310

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