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Using high-throughput barcode sequencing to efficiently map connectomes

The function of a neural circuit is determined by the details of its synaptic connections. At present, the only available method for determining a neural wiring diagram with single synapse precision—a ‘connectome’—is based on imaging methods that are slow, labor-intensive and expensive. Here, we pre...

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Detalles Bibliográficos
Autores principales: Peikon, Ian D., Kebschull, Justus M., Vagin, Vasily V., Ravens, Diana I., Sun, Yu-Chi, Brouzes, Eric, Corrêa, Ivan R., Bressan, Dario, Zador, Anthony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499584/
https://www.ncbi.nlm.nih.gov/pubmed/28449067
http://dx.doi.org/10.1093/nar/gkx292