A Benzylideneacetophenone Derivative Induces Apoptosis of Radiation-Resistant Human Breast Cancer Cells via Oxidative Stress

Benzylideneacetophenone derivative (1E)-1-(4-hydroxy-3-methoxyphenyl) hept-1-en-3-one (JC3) elicited cytotoxic effects on MDA-MB 231 human breast cancer cells-radiation resistant cells (MDA-MB 231-RR), in a dose-dependent manner, with an IC(50) value of 6 μM JC3. JC3-mediated apoptosis was confirmed...

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Detalles Bibliográficos
Autores principales: Park, Jeong Eon, Piao, Mei Jing, Kang, Kyoung Ah, Shilnikova, Kristina, Hyun, Yu Jae, Oh, Sei Kwan, Jeong, Yong Joo, Chae, Sungwook, Hyun, Jin Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499619/
https://www.ncbi.nlm.nih.gov/pubmed/28554201
http://dx.doi.org/10.4062/biomolther.2017.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499619/
https://www.ncbi.nlm.nih.gov/pubmed/28554201
http://dx.doi.org/10.4062/biomolther.2017.010

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