Cargando…

A Benzylideneacetophenone Derivative Induces Apoptosis of Radiation-Resistant Human Breast Cancer Cells via Oxidative Stress

Benzylideneacetophenone derivative (1E)-1-(4-hydroxy-3-methoxyphenyl) hept-1-en-3-one (JC3) elicited cytotoxic effects on MDA-MB 231 human breast cancer cells-radiation resistant cells (MDA-MB 231-RR), in a dose-dependent manner, with an IC(50) value of 6 μM JC3. JC3-mediated apoptosis was confirmed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Jeong Eon, Piao, Mei Jing, Kang, Kyoung Ah, Shilnikova, Kristina, Hyun, Yu Jae, Oh, Sei Kwan, Jeong, Yong Joo, Chae, Sungwook, Hyun, Jin Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499619/ https://www.ncbi.nlm.nih.gov/pubmed/28554201 http://dx.doi.org/10.4062/biomolther.2017.010

Ejemplares similares

Shikonin induces mitochondria-mediated apoptosis and attenuates epithelial-mesenchymal transition in cisplatin-resistant human ovarian cancer cells
por: Shilnikova, Kristina, et al.
Publicado: (2018)

Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis
por: Piao, Mei Jing, et al.
Publicado: (2018)

The Red Algae Compound 3-Bromo-4,5-dihydroxybenzaldehyde Protects Human Keratinocytes on Oxidative Stress-Related Molecules and Pathways Activated by UVB Irradiation
por: Piao, Mei Jing, et al.
Publicado: (2017)

Natural Compound Shikonin Induces Apoptosis and Attenuates Epithelial to Mesenchymal Transition in Radiation-Resistant Human Colon Cancer Cells
por: Shilnikova, Kristina, et al.
Publicado: (2022)

Protective Effect of an Isoflavone, Tectorigenin, Against Oxidative Stress-induced Cell Death via Catalase Activation
por: Zhang, Rui, et al.
Publicado: (2016)

JC2-11, a benzylideneacetophenone derivative, attenuates inflammasome activation
por: Lee, Gilyoung, et al.
Publicado: (2022)

Benzylideneacetophenone Derivative Alleviates Arthritic Symptoms via Modulation of the MAPK Signaling Pathway
por: Sur, Bongjun, et al.
Publicado: (2020)

Reduced Autophagy in 5-Fluorouracil Resistant Colon Cancer Cells
por: Yao, Cheng Wen, et al.
Publicado: (2017)

Galangin Activates the ERK/AKT-Driven Nrf2 Signaling Pathway to Increase the Level of Reduced Glutathione in Human Keratinocytes
por: Hewage, Susara Ruwan Kumara Madduma, et al.
Publicado: (2017)

DUOX2-mediated production of reactive oxygen species induces epithelial mesenchymal transition in 5-fluorouracil resistant human colon cancer cells
por: Kang, Kyoung Ah, et al.
Publicado: (2018)

Purpurogallin Protects Keratinocytes from Damage and Apoptosis Induced by Ultraviolet B Radiation and Particulate Matter 2.5
por: Zhen, Ao Xuan, et al.
Publicado: (2019)

Benzylideneacetophenone derivatives attenuate IFN-γ-induced IP-10/CXCL10 production in orbital fibroblasts of patients with thyroid-associated ophthalmopathy through STAT-1 inhibition
por: Lee, Sung-Hee, et al.
Publicado: (2014)

Protective Effect of Fisetin (3,7,3',4'-Tetrahydroxyflavone) against γ-Irradiation-Induced Oxidative Stress and Cell Damage
por: Piao, Mei Jing, et al.
Publicado: (2013)

Hesperidin Attenuates Ultraviolet B-Induced Apoptosis by Mitigating Oxidative Stress in Human Keratinocytes
por: Hewage, Susara Ruwan Kumara Madduma, et al.
Publicado: (2016)

Inhibition of Carrageenan/Kaolin-Induced Arthritis in Rats and of Inflammatory Cytokine Expressions in Human IL-1β-Stimulated Fibroblast-like Synoviocytes by a Benzylideneacetophenone Derivative
por: Sur, Bongjun, et al.
Publicado: (2018)

Rosmarinic Acid Attenuates Cell Damage against UVB Radiation-Induced Oxidative Stress via Enhancing Antioxidant Effects in Human HaCaT Cells
por: Fernando, Pattage Madushan Dilhara Jayatissa, et al.
Publicado: (2016)

Galangin (3,5,7-Trihydroxyflavone) Shields Human Keratinocytes from Ultraviolet B-Induced Oxidative Stress
por: Madduma Hewage, Susara Ruwan Kumara, et al.
Publicado: (2015)

Anti-wrinkle effects of Sargassum muticum ethyl acetate fraction on ultraviolet B-irradiated hairless mouse skin and mechanistic evaluation in the human HaCaT keratinocyte cell line
por: Song, Jae Hyoung, et al.
Publicado: (2016)

Hesperidin Protects Human HaCaT Keratinocytes from Particulate Matter 2.5-Induced Apoptosis via the Inhibition of Oxidative Stress and Autophagy
por: Fernando, Pincha Devage Sameera Madushan, et al.
Publicado: (2022)

Dictyopteris undulata Extract Induces Apoptosis via Induction of Endoplasmic Reticulum Stress in Human Colon Cancer Cells
por: Kang, Kyoung Ah, et al.
Publicado: (2014)

Triphlorethol-A from Ecklonia cava Up-Regulates the Oxidant Sensitive 8-Oxoguanine DNA Glycosylase 1
por: Kim, Ki Cheon, et al.
Publicado: (2014)

Butin (7,3′,4′-Trihydroxydihydroflavone) Reduces Oxidative Stress-Induced Cell Death via Inhibition of the Mitochondria-Dependent Apoptotic Pathway
por: Zhang, Rui, et al.
Publicado: (2011)

Niacinamide Protects Skin Cells from Oxidative Stress Induced by Particulate Matter
por: Zhen, Ao Xuan, et al.
Publicado: (2019)

Myricetin Protects Cells against Oxidative Stress-Induced Apoptosis via Regulation of PI3K/Akt and MAPK Signaling Pathways
por: Kang, Kyoung Ah, et al.
Publicado: (2010)

Particulate matter-induced senescence of skin keratinocytes involves oxidative stress-dependent epigenetic modifications
por: Ryu, Yea Seong, et al.
Publicado: (2019)

7,8-Dihydroxyflavone Suppresses Oxidative Stress-Induced Base Modification in DNA via Induction of the Repair Enzyme 8-Oxoguanine DNA Glycosylase-1
por: Kim, Ki Cheon, et al.
Publicado: (2013)

Baicalein Protects Human Skin Cells against Ultraviolet B-Induced Oxidative Stress
por: Oh, Min Chang, et al.
Publicado: (2016)

Fucoxanthin Protects Cultured Human Keratinocytes against Oxidative Stress by Blocking Free Radicals and Inhibiting Apoptosis
por: Zheng, Jian, et al.
Publicado: (2013)

Horse Oil Mitigates Oxidative Damage to Human HaCaT Keratinocytes Caused by Ultraviolet B Irradiation
por: Piao, Mei Jing, et al.
Publicado: (2019)

Protective Effect of Diphlorethohydroxycarmalol against Ultraviolet B Radiation-Induced DNA Damage by Inducing the Nucleotide Excision Repair System in HaCaT Human Keratinocytes
por: Piao, Mei Jing, et al.
Publicado: (2015)

The Endoplasmic Reticulum Stress Response Mediates Shikonin-Induced Apoptosis of 5-Fluorouracil–Resistant Colorectal Cancer Cells
por: Piao, Mei Jing, et al.
Publicado: (2022)

7,8-Dihydroxyflavone Protects High Glucose-Damaged Neuronal Cells against Oxidative Stress
por: Cho, Suk Ju, et al.
Publicado: (2019)

The role of adjuvant external beam radiation therapy for papillary thyroid carcinoma invading the trachea
por: Kim, Young Suk, et al.
Publicado: (2017)

Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells
por: Kang, Kyoung Ah, et al.
Publicado: (2019)

Hyperoside Induces Endogenous Antioxidant System to Alleviate Oxidative Stress
por: Park, Ji Young, et al.
Publicado: (2016)

Fucodiphlorethol G Purified from Ecklonia cava Suppresses Ultraviolet B Radiation-Induced Oxidative Stress and Cellular Damage
por: Kim, Ki Cheon, et al.
Publicado: (2014)

Assessment of the 4‐week repeated‐dose oral toxicity and genotoxicity of GHX02
por: Ji, Kon‐Young, et al.
Publicado: (2019)

Non-thermal dielectric-barrier discharge plasma damages human keratinocytes by inducing oxidative stress
por: KIM, KI CHEON, et al.
Publicado: (2016)

Correction: Kang, K.A.; et al., Myricetin Protects Cells against Oxidative Stress-Induced Apoptosis via Regulation of PI3K/Akt and MAPK Signaling Pathways. Int. J. Mol. Sci. 2010, 11, 4348–4360
por: Kang, Kyoung Ah, et al.
Publicado: (2015)

Oxidative Stress, Nrf2, and Epigenetic Modification Contribute to Anticancer Drug Resistance
por: Kang, Kyoung Ah, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_78sqeke94jodl5p2367l035g8o