Replication and repair of a reduced 2΄-deoxyguanosine-abasic site interstrand cross-link in human cells

Apurinic/apyrimidinic (AP) sites, or abasic sites, which are a common type of endogenous DNA damage, can forge interstrand DNA–DNA cross-links via reaction with the exocyclic amino group on a nearby 2΄-deoxyguanosine or 2΄-deoxyadenosine in the opposite strand. Here, we utilized a shuttle vector met...

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Detalles Bibliográficos
Autores principales: Price, Nathan E., Li, Lin, Gates, Kent S., Wang, Yinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499640/
https://www.ncbi.nlm.nih.gov/pubmed/28431012
http://dx.doi.org/10.1093/nar/gkx266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499640/
https://www.ncbi.nlm.nih.gov/pubmed/28431012
http://dx.doi.org/10.1093/nar/gkx266

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