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Critical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain

The nascent peptide exit tunnel has recently been identified as a functional region of ribosomes contributing to translation regulation and co-translational protein folding. Inducible expression of the erm resistance genes depends on ribosome stalling at specific codons of an upstream open reading f...

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Detalles Bibliográficos
Autores principales: Koch, Miriam, Willi, Jessica, Pradère, Ugo, Hall, Jonathan, Polacek, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499644/
https://www.ncbi.nlm.nih.gov/pubmed/28369621
http://dx.doi.org/10.1093/nar/gkx195