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The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD(2)-(c-di-GMP)(4) complex
Streptomyces are ubiquitous soil bacteria that undergo a complex developmental transition coinciding with their production of antibiotics. This transition is controlled by binding of a novel tetrameric form of the second messenger, 3΄-5΄ cyclic diguanylic acid (c-di-GMP) to the master repressor, Bld...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499655/ https://www.ncbi.nlm.nih.gov/pubmed/28449057 http://dx.doi.org/10.1093/nar/gkx287 |