The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD(2)-(c-di-GMP)(4) complex

Streptomyces are ubiquitous soil bacteria that undergo a complex developmental transition coinciding with their production of antibiotics. This transition is controlled by binding of a novel tetrameric form of the second messenger, 3΄-5΄ cyclic diguanylic acid (c-di-GMP) to the master repressor, Bld...

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Detalles Bibliográficos
Autores principales: Schumacher, Maria A., Zeng, Wenjie, Findlay, Kim C., Buttner, Mark J., Brennan, Richard G., Tschowri, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499655/
https://www.ncbi.nlm.nih.gov/pubmed/28449057
http://dx.doi.org/10.1093/nar/gkx287

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