BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation

Mutations in SOX10 cause neurocristopathies which display varying degrees of hypopigmentation. Using a sensitized mutagenesis screen, we identified Smarca4 as a modifier gene that exacerbates the phenotypic severity of Sox10 haplo-insufficient mice. Conditional deletion of Smarca4 in SOX10 expressin...

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Detalles Bibliográficos
Autores principales: Marathe, Himangi G., Watkins-Chow, Dawn E., Weider, Matthias, Hoffmann, Alana, Mehta, Gaurav, Trivedi, Archit, Aras, Shweta, Basuroy, Tupa, Mehrotra, Aanchal, Bennett, Dorothy C., Wegner, Michael, Pavan, William J., de la Serna, Ivana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499657/
https://www.ncbi.nlm.nih.gov/pubmed/28431046
http://dx.doi.org/10.1093/nar/gkx259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499657/
https://www.ncbi.nlm.nih.gov/pubmed/28431046
http://dx.doi.org/10.1093/nar/gkx259

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