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A novel rare sugar inhibitor of murine herpes simplex keratitis

PURPOSE: To determine the therapeutic efficacy of a novel rare sugar, L-psicose, for the treatment of HSV-1 induced herpetic stromal keratitis (HSK) in a mouse eye model. METHODS: One rare sugar L-psicose was assayed for HSV-1 inhibition of in vitro virus adsorption. The IC(50) and IC(90) values of...

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Detalles Bibliográficos
Autores principales: Muniruzzaman, Syed, McIntosh, Megan, Hossain, Ahamed, Izumori, Ken, Bhattacharjee, Partha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499707/
https://www.ncbi.nlm.nih.gov/pubmed/27262904
http://dx.doi.org/10.1016/j.jphs.2016.05.004