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A novel rare sugar inhibitor of murine herpes simplex keratitis
PURPOSE: To determine the therapeutic efficacy of a novel rare sugar, L-psicose, for the treatment of HSV-1 induced herpetic stromal keratitis (HSK) in a mouse eye model. METHODS: One rare sugar L-psicose was assayed for HSV-1 inhibition of in vitro virus adsorption. The IC(50) and IC(90) values of...
Autores principales: | Muniruzzaman, Syed, McIntosh, Megan, Hossain, Ahamed, Izumori, Ken, Bhattacharjee, Partha S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499707/ https://www.ncbi.nlm.nih.gov/pubmed/27262904 http://dx.doi.org/10.1016/j.jphs.2016.05.004 |
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