Design of Radioiodinated Pharmaceuticals: Structural Features Affecting Metabolic Stability towards in Vivo Deiodination

Radioiodinated pharmaceuticals are convenient tracers for clinical and research investigations because of the relatively long half‐lives of radioactive iodine isotopes (i.e., (123)I, (124)I, and (131)I) and the ease of their chemical insertion. Their application in radionuclide imaging and therapy m...

Descripción completa

Detalles Bibliográficos
Autores principales: Cavina, Lorenzo, van der Born, Dion, Klaren, Peter H. M., Feiters, Martin C., Boerman, Otto C., Rutjes, Floris P. J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Microreview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499721/
https://www.ncbi.nlm.nih.gov/pubmed/28736501
http://dx.doi.org/10.1002/ejoc.201601638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499721/
https://www.ncbi.nlm.nih.gov/pubmed/28736501
http://dx.doi.org/10.1002/ejoc.201601638

Ejemplares similares