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Potent DNA strand annealing activity associated with mouse Mcm2∼7 heterohexameric complex

Mini-chromosome maintenance (Mcm) is a central component for DNA unwinding reaction during eukaryotic DNA replication. Mcm2∼7, each containing a conserved ATPase motif, form a six subunit-heterohexamer. Although the reconstituted Mcm2∼7–Cdc45–GINS (CMG) complex displays DNA unwinding activity, the M...

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Detalles Bibliográficos
Autores principales: You, Zhiying, Masai, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499727/
https://www.ncbi.nlm.nih.gov/pubmed/28449043
http://dx.doi.org/10.1093/nar/gkx269