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Nonsense-mediated mRNA decay in Tetrahymena is EJC independent and requires a protozoa-specific nuclease

Nonsense-mediated mRNA decay (NMD) is essential for removing premature termination codon-containing transcripts from cells. Studying the NMD pathway in model organisms can help to elucidate the NMD mechanism in humans and improve our understanding of how this biologically important process has evolv...

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Detalles Bibliográficos
Autores principales: Tian, Miao, Yang, Wentao, Zhang, Jing, Dang, Huai, Lu, Xingyi, Fu, Chengjie, Miao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499736/
https://www.ncbi.nlm.nih.gov/pubmed/28402567
http://dx.doi.org/10.1093/nar/gkx256