An RRM–ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion

RBM10 is an RNA-binding protein that plays an essential role in development and is frequently mutated in the context of human disease. RBM10 recognizes a diverse set of RNA motifs in introns and exons and regulates alternative splicing. However, the molecular mechanisms underlying this seemingly rel...

Descripción completa

Detalles Bibliográficos
Autores principales: Collins, Katherine M., Kainov, Yaroslav A., Christodolou, Evangelos, Ray, Debashish, Morris, Quaid, Hughes, Timothy, Taylor, Ian A., Makeyev, Eugene V., Ramos, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499739/
https://www.ncbi.nlm.nih.gov/pubmed/28379442
http://dx.doi.org/10.1093/nar/gkx225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499739/
https://www.ncbi.nlm.nih.gov/pubmed/28379442
http://dx.doi.org/10.1093/nar/gkx225

Ejemplares similares