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An RRM–ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion

RBM10 is an RNA-binding protein that plays an essential role in development and is frequently mutated in the context of human disease. RBM10 recognizes a diverse set of RNA motifs in introns and exons and regulates alternative splicing. However, the molecular mechanisms underlying this seemingly rel...

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Detalles Bibliográficos
Autores principales:	Collins, Katherine M., Kainov, Yaroslav A., Christodolou, Evangelos, Ray, Debashish, Morris, Quaid, Hughes, Timothy, Taylor, Ian A., Makeyev, Eugene V., Ramos, Andres
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499739/ https://www.ncbi.nlm.nih.gov/pubmed/28379442 http://dx.doi.org/10.1093/nar/gkx225

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