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Predicting the impact of non-coding variants on DNA methylation

DNA methylation plays a crucial role in the establishment of tissue-specific gene expression and the regulation of key biological processes. However, our present inability to predict the effect of genome sequence variation on DNA methylation precludes a comprehensive assessment of the consequences o...

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Detalles Bibliográficos
Autores principales: Zeng, Haoyang, Gifford, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499808/
https://www.ncbi.nlm.nih.gov/pubmed/28334830
http://dx.doi.org/10.1093/nar/gkx177