SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms

The SeqA protein binds hemi-methylated GATC sites and forms structures that sequester newly replicated origins and trail the replication forks. Cells that lack SeqA display signs of replication fork disintegration. The broken forks could arise because of over-initiation (the launching of too many fo...

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Detalles Bibliográficos
Autores principales: Pedersen, Ida Benedikte, Helgesen, Emily, Flåtten, Ingvild, Fossum-Raunehaug, Solveig, Skarstad, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499823/
https://www.ncbi.nlm.nih.gov/pubmed/28407100
http://dx.doi.org/10.1093/nar/gkx263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499823/
https://www.ncbi.nlm.nih.gov/pubmed/28407100
http://dx.doi.org/10.1093/nar/gkx263

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