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Structural basis for substrate binding and catalytic mechanism of a human RNA:m(5)C methyltransferase NSun6

5-methylcytosine (m(5)C) modifications of RNA are ubiquitous in nature and play important roles in many biological processes such as protein translational regulation, RNA processing and stress response. Aberrant expressions of RNA:m(5)C methyltransferases are closely associated with various human di...

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Detalles Bibliográficos
Autores principales: Liu, Ru-Juan, Long, Tao, Li, Jing, Li, Hao, Wang, En-Duo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499824/
https://www.ncbi.nlm.nih.gov/pubmed/28531330
http://dx.doi.org/10.1093/nar/gkx473