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Structural basis for substrate binding and catalytic mechanism of a human RNA:m(5)C methyltransferase NSun6
5-methylcytosine (m(5)C) modifications of RNA are ubiquitous in nature and play important roles in many biological processes such as protein translational regulation, RNA processing and stress response. Aberrant expressions of RNA:m(5)C methyltransferases are closely associated with various human di...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499824/ https://www.ncbi.nlm.nih.gov/pubmed/28531330 http://dx.doi.org/10.1093/nar/gkx473 |