The non-stop decay mRNA surveillance pathway is required for oxidative stress tolerance

Reactive oxygen species (ROS) are toxic by-products of normal aerobic metabolism. ROS can damage mRNAs and the translational apparatus resulting in translational defects and aberrant protein production. Three mRNA quality control systems monitor mRNAs for translational errors: nonsense-mediated deca...

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Detalles Bibliográficos
Autores principales: Jamar, Nur H., Kritsiligkou, Paraskevi, Grant, Chris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499853/
https://www.ncbi.nlm.nih.gov/pubmed/28472342
http://dx.doi.org/10.1093/nar/gkx306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499853/
https://www.ncbi.nlm.nih.gov/pubmed/28472342
http://dx.doi.org/10.1093/nar/gkx306

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