Mechanism of bacterial gene rearrangement: SprA-catalyzed precise DNA recombination and its directionality control by SprB ensure the gene rearrangement and stable expression of spsM during sporulation in Bacillus subtilis

A sporulation-specific gene, spsM, is disrupted by an active prophage, SPβ, in the genome of Bacillus subtilis. SPβ excision is required for two critical steps: the onset of the phage lytic cycle and the reconstitution of the spsM-coding frame during sporulation. Our in vitro study demonstrated that...

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Detalles Bibliográficos
Autores principales: Abe, Kimihiro, Takamatsu, Takuo, Sato, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499854/
https://www.ncbi.nlm.nih.gov/pubmed/28535266
http://dx.doi.org/10.1093/nar/gkx466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499854/
https://www.ncbi.nlm.nih.gov/pubmed/28535266
http://dx.doi.org/10.1093/nar/gkx466

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