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Targeted regulation of MiR-98 on E2F1 increases chemosensitivity of leukemia cells K562/A02

BACKGROUND: miRNA is a microRNA that negatively regulates protein expression at post-transcriptional or translational level. It is widely involved in the pathogenesis of tumors. miR-98 belongs to the let-7 family, and its overexpression can increase the sensitivity to drugs in solid cancer cells. Ho...

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Detalles Bibliográficos
Autores principales: Huang, Yingdan, Hong, Xiuli, Hu, Jiasheng, Lu, Quanyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499860/
https://www.ncbi.nlm.nih.gov/pubmed/28721074
http://dx.doi.org/10.2147/OTT.S126819