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Targeted regulation of MiR-98 on E2F1 increases chemosensitivity of leukemia cells K562/A02
BACKGROUND: miRNA is a microRNA that negatively regulates protein expression at post-transcriptional or translational level. It is widely involved in the pathogenesis of tumors. miR-98 belongs to the let-7 family, and its overexpression can increase the sensitivity to drugs in solid cancer cells. Ho...
Autores principales: | Huang, Yingdan, Hong, Xiuli, Hu, Jiasheng, Lu, Quanyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499860/ https://www.ncbi.nlm.nih.gov/pubmed/28721074 http://dx.doi.org/10.2147/OTT.S126819 |
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