CXCL12 suppresses cisplatin-induced apoptosis through activation of JAK2/STAT3 signaling in human non-small-cell lung cancer cells

AIMS: Poor efficacy of chemotherapy drugs in non-small-cell lung cancer (NSCLC) is the key reason for the failure of treatment, but the mechanism of this remains largely unknown. Stromal cell-derived factor 1-alpha (SDF-1α/CXCL12) is a small chemotactic cytokine protein that plays an important role...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Lin, Tie, Wang, Yicun, Gao, Song, Yang, Zhaoyang, Hong, Xuan, Chen, Gongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499863/
https://www.ncbi.nlm.nih.gov/pubmed/28721072
http://dx.doi.org/10.2147/OTT.S133055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499863/
https://www.ncbi.nlm.nih.gov/pubmed/28721072
http://dx.doi.org/10.2147/OTT.S133055

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