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CXCL12 suppresses cisplatin-induced apoptosis through activation of JAK2/STAT3 signaling in human non-small-cell lung cancer cells

AIMS: Poor efficacy of chemotherapy drugs in non-small-cell lung cancer (NSCLC) is the key reason for the failure of treatment, but the mechanism of this remains largely unknown. Stromal cell-derived factor 1-alpha (SDF-1α/CXCL12) is a small chemotactic cytokine protein that plays an important role...

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Detalles Bibliográficos
Autores principales:	Wang, Meng, Lin, Tie, Wang, Yicun, Gao, Song, Yang, Zhaoyang, Hong, Xuan, Chen, Gongyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499863/ https://www.ncbi.nlm.nih.gov/pubmed/28721072 http://dx.doi.org/10.2147/OTT.S133055

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