Cargando…

Heat shock factor 1 promotes TERRA transcription and telomere protection upon heat stress

In response to metabolic or environmental stress, cells activate powerful defense mechanisms to prevent the formation and accumulation of toxic protein aggregates. The main orchestrator of this cellular response is HSF1 (heat shock factor 1), a transcription factor involved in the up-regulation of p...

Descripción completa

Detalles Bibliográficos
Autores principales: Koskas, Sivan, Decottignies, Anabelle, Dufour, Solenne, Pezet, Mylène, Verdel, André, Vourc’h, Claire, Faure, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499866/
https://www.ncbi.nlm.nih.gov/pubmed/28369628
http://dx.doi.org/10.1093/nar/gkx208