The effect of increasing numbers of repeats on TAL effector DNA binding specificity

Transcription activator-like effectors (TALEs) recognize their DNA targets via tandem repeats, each specifying a single nucleotide base in a one-to-one sequential arrangement. Due to this modularity and their ability to bind long DNA sequences with high specificity, TALEs have been used in many appl...

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Detalles Bibliográficos
Autores principales: Rinaldi, Fabio C., Doyle, Lindsey A., Stoddard, Barry L., Bogdanove, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499867/
https://www.ncbi.nlm.nih.gov/pubmed/28460076
http://dx.doi.org/10.1093/nar/gkx342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499867/
https://www.ncbi.nlm.nih.gov/pubmed/28460076
http://dx.doi.org/10.1093/nar/gkx342

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