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The effect of increasing numbers of repeats on TAL effector DNA binding specificity
Transcription activator-like effectors (TALEs) recognize their DNA targets via tandem repeats, each specifying a single nucleotide base in a one-to-one sequential arrangement. Due to this modularity and their ability to bind long DNA sequences with high specificity, TALEs have been used in many appl...
Autores principales: | Rinaldi, Fabio C., Doyle, Lindsey A., Stoddard, Barry L., Bogdanove, Adam J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499867/ https://www.ncbi.nlm.nih.gov/pubmed/28460076 http://dx.doi.org/10.1093/nar/gkx342 |
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