SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing

Pre-mRNA splicing is catalyzed by the spliceosome, a multi-megadalton ribonucleoprotein machine. Previous work from our laboratory revealed the splicing factor SRSF1 as a regulator of the SUMO pathway, leading us to explore a connection between this pathway and the splicing machinery. We show here t...

Descripción completa

Detalles Bibliográficos
Autores principales: Pozzi, Berta, Bragado, Laureano, Will, Cindy L., Mammi, Pablo, Risso, Guillermo, Urlaub, Henning, Lührmann, Reinhard, Srebrow, Anabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499870/
https://www.ncbi.nlm.nih.gov/pubmed/28379520
http://dx.doi.org/10.1093/nar/gkx213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499870/
https://www.ncbi.nlm.nih.gov/pubmed/28379520
http://dx.doi.org/10.1093/nar/gkx213

Ejemplares similares