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SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing

Pre-mRNA splicing is catalyzed by the spliceosome, a multi-megadalton ribonucleoprotein machine. Previous work from our laboratory revealed the splicing factor SRSF1 as a regulator of the SUMO pathway, leading us to explore a connection between this pathway and the splicing machinery. We show here t...

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Detalles Bibliográficos
Autores principales:	Pozzi, Berta, Bragado, Laureano, Will, Cindy L., Mammi, Pablo, Risso, Guillermo, Urlaub, Henning, Lührmann, Reinhard, Srebrow, Anabella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499870/ https://www.ncbi.nlm.nih.gov/pubmed/28379520 http://dx.doi.org/10.1093/nar/gkx213

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