Combination therapeutics of Nilotinib and radiation in acute lymphoblastic leukemia as an effective method against drug-resistance

Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) is characterized by a very poor prognosis and a high likelihood of acquired chemo-resistance. Although tyrosine kinase inhibitor (TKI) therapy has improved clinical outcome, most ALL patients relapse following treatment with T...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaveh, Kamran, Takahashi, Yutaka, Farrar, Michael A., Storme, Guy, Guido, Marcucci, Piepenburg, Jamie, Penning, Jackson, Foo, Jasmine, Leder, Kevin Z., Hui, Susanta K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500007/
https://www.ncbi.nlm.nih.gov/pubmed/28683103
http://dx.doi.org/10.1371/journal.pcbi.1005482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500007/
https://www.ncbi.nlm.nih.gov/pubmed/28683103
http://dx.doi.org/10.1371/journal.pcbi.1005482

Ejemplares similares