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Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires
The diversity of T-cell receptors recognizing foreign pathogens is generated through a highly stochastic recombination process, making the independent production of the same sequence rare. Yet unrelated individuals do share receptors, which together constitute a “public” repertoire of abundant clono...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500008/ https://www.ncbi.nlm.nih.gov/pubmed/28683116 http://dx.doi.org/10.1371/journal.pcbi.1005572 |